Our paper with the Knudsen group on filtering mouse contamination from genome sequences of xenograft tumors is now in press at Bioinformatics. Congratulations to Brian!
Our department head, Joyce Schroeder, had the wonderful idea to engage some of UA’s fine arts students to represent our department’s research. I particularly like Elena Makansi‘s representation of our work!
Our recent work with Erik Knudsen on variant calling in tumors is now on bioRxiv. The paper introduces a new approach for analyzing genetic variants called from next-gen sequencing of tumors. A key challenge in such sequencing is spurious variants calls, particularly when sequencing tumors that have been xenografted into mice. We introduce and characterize a… Read More »
Our collaborative paper with Michael Hammer on polygenic adaptation in Siberians has been published in MBE. In the paper, we develop a comprehensive model of the join demographic history of Europeans, East Asians, and Siberians. We then use that model as a null model to scan for gene sets enriched in signatures of population-specific adaptation. Three… Read More »
Ryan is please to announce that he has been promoted to Associate Professor with tenure. He gives his heartfelt thanks all his current and former students and postdocs. They truly accomplish the groups’ research, and mentoring them is the best part of his job. He also thanks all his colleagues: within MCB, the University of Arizona,… Read More »