Congratulations to Brian Mannakee on his paper that just came out in PLoS Genetics. In it, we use dynamical systems biology models to predict rates of protein domain evolution. The success of these predictions suggests that natural selection is acting to preserve network dynamics in the face of perturbations from mutations. Although the models are… Read More »
Congratulations to Aaron Ragsdale on his paper that was just accepted for publication in Genetics. In it, we develop a novel diffusion model for trialleic sites, which required some non-trivial applied mathematics. We then apply the model to mutually nonsynonymous codons in Drosophila, to infer the correlation between selection coefficients for mutations at the same… Read More »
Congratulations to Benson Hsieh on defending his Ph.D. thesis! Benson will be starting a postdoc in the laboratory of Evan Eichler in the summer.
Ryan had a wonderful time teaching at the 2016 Workshop on Population and Speciation Genomics in Cesky Krumlov, Czech Republic. Ryan lectured about demographic inference and ran tutorials on Python programming and using ∂a∂i. The slides and exercises he developed are available here.
Congratulations to Benson Hsieh on his two papers that were recently accepted for publication in Genome Research. Both result from our close collaboration with Michael Hammer, Benon’s PhD co-supervisor. In the first paper, we infer a complex demographic model for Central African Pygmies and neighboring farmers. We then use that model as the basis for whole-genome neutral… Read More »